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Thyroid-Related Concerns : Although primarily observed in rodent studies, tirzepatide carries a boxed warning regarding thyroid C-cell tumors

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Atomic model refinement The initial template for the AMYR:Cagri/CagriBB complex was generated by changing the divergent resides of rAmy in the corresponding AMYR:rAmy complex (PDB: 7TYF,7TYX, 7TZF)